Symbol
Name
ID

Piga
phosphatidylinositol glycan anchor biosynthesis, class A
MGI:99461

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes

Pancytopenia

Abnormal erythrocyte enzyme concentration or activity

Erythroid hyperplasia

Reticulocytosis

Anemia

Hemolytic anemia

Leukopenia

Arterial thrombosis

Thromboembolism

Venous thrombosis

Deep venous thrombosis

Mesenteric venous thrombosis

Thrombocytopenia

Disease(s) Associated with PIGA

paroxysmal nocturnal hemoglobinuria

Mouse Phenotypes		abnormal definitive hematopoiesis	abnormal erythrocyte morphology	decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	reticulocytosis	abnormal T cell morphology	abnormal erythrocyte physiology	increased erythrocyte osmotic fragility	abnormal T cell physiology	abnormal T cell activation
Availability	Mouse Genotype	abnormal definitive hematopoiesis	abnormal erythrocyte morphology		reticulocytosis	abnormal T cell morphology	abnormal erythrocyte physiology	increased erythrocyte osmotic fragility	abnormal T cell physiology	abnormal T cell activation
	Piga^tm1Tak/Piga^tm1Tak Tg(FES-cre)31Bsl/0 (conditional)
	Piga^tm1Bsl/Piga⁺ Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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